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AbbVie Q3 2026 Earnings Preview: ABBV Results and Outlook

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AbbVie (ABBV) — Q3 2026 Earnings Preview

Key Points

ThemeDetails
Consensus ExpectationsQ3 2026 revenue consensus: $17,307M; EPS consensus: $2.39 (GAAP)
GuidanceFY 2026 revenue guidance raised to $67,600M (as of Q2 call); Q3 revenue guidance: $17,200M
Recent PerformanceQ2 2026 revenue: $16,976M (+10.2% YoY); Adjusted EPS: $3.65; strong double-digit growth in Skyrizi, Rinvoq, and neuroscience
Key Watch Items for Q3
  • Uptake and momentum in Skyrizi and Rinvoq (immunology)
  • Neuroscience portfolio growth (Vraylar, Botox Therapeutic, Ubrelvy, Qulipta, Vyalev)
  • Approval and launch trajectory for Skyrizi subcutaneous induction in Crohn’s
  • Progress on Apogee Therapeutics acquisition and pipeline integration
  • Hidradenitis suppurativa (HS) Phase III readouts for lutikizumab and Rinvoq
  • Oncology pipeline updates (Temab-A, etentamig, PD-1/VEGF, etc.)
ComparablesQ3 2025 revenue: $15,586M; Q3 2025 adjusted EPS: $1.86
YoY CompQ3 2026 faces a relatively easy comp (+11% YoY consensus growth expected)

Most Important Factors to Watch This Quarter

FactorWhy It Matters
Skyrizi & Rinvoq GrowthBoth are core to AbbVie’s immunology franchise; consensus expects >20% YoY growth to continue
Neuroscience OutperformanceSegment is now a key pillar (Vraylar, migraine, Parkinson’s); watch for continued double-digit growth
Skyrizi Subcu Induction ApprovalFDA decision expected in Q4, but any update on timing or launch plans will be closely watched
Apogee Therapeutics IntegrationProgress on closing and pipeline prioritization; clarity on Zumi (zumilokibart) Phase III timelines
HS Readouts (Lutikizumab, Rinvoq)Data expected in 2H26; could set up new growth drivers in underpenetrated dermatology market
Oncology Pipeline UpdatesTemab-A, etentamig, and other ADCs/TCEs are potential long-term growth drivers; IMS/ASCO data flow
Margin ExpansionOperating leverage as revenue grows; consensus expects op margin near 47% for FY26
Pricing/Access DynamicsImmunology pricing remains “low single-digit” headwind; payer negotiations for 2027 underway
Guidance RevisionsManagement has raised FY guidance twice YTD; further upward revisions would be a positive signal

Recent Results and Forward Consensus

Quarterly Financials (Actuals and Consensus)

QuarterRevenue ($M)YoY GrowthAdj. EPSYoY GrowthNotes
Q2 202616,976+10.2%3.65+13.2%Beat by $300M vs. guidance
Q1 202615,000+12.4%2.65+10.4%Beat by $300M vs. guidance
Q4 202516,415+10.0%2.71+8.0%
Q3 202515,586+8.4%1.86+5.7%
Q3 2026E17,307+11.0%2.39+28.5%Consensus (GAAP EPS)
Q4 2026E18,319+11.6%2.96+23.8%Consensus (GAAP EPS)

Note: Adjusted EPS figures are from company guidance and transcripts; consensus EPS is GAAP.


Full-Year Guidance and Consensus

MetricFY 2026 Guidance (Q2)FY 2026 ConsensusFY 2025 ActualYoY Growth (Guidance)
Revenue ($M)67,60067,60061,200+10.5%
Adj. EPS13.87–14.07
10.00+39% at midpoint
Op Margin (%)~47%
41%+600 bps

Segment Trends and KPIs

SegmentQ2 2026 Sales ($M)YoY GrowthKey Commentary
Immunology8,800+14.6%Skyrizi $5.5B (+24%), Rinvoq $2.5B (+23.7%)
Neuroscience3,200+20%Vraylar, Botox Therapeutic, Ubrelvy, Qulipta, Vyalev
Oncology1,600-2.4%Venclexta up, Imbruvica down, new launches ongoing
Aesthetics1,300-0.9%Botox Cosmetic up, Juvederm down

How Did They Report Last Year? (Q3 2025)

MetricQ3 2025 ActualYoY GrowthNotes
Revenue ($M)15,586+8.4%Beat expectations by ~$300M
Adj. EPS1.86+5.7%$0.10 above guidance midpoint
Skyrizi Sales4,700+46%Strong IBD/psoriasis growth
Rinvoq Sales2,200+34%Gastro/RA/derm momentum
Neuroscience2,800+19.6%Migraine, Vraylar, Vyalev outperforming
Oncology1,700FlatImbruvica down, new launches offsetting
Aesthetics1,200-4.2%Market softness, especially fillers

Comp: Q3 2025 was a strong quarter with high single-digit growth, but Q3 2026 consensus implies an acceleration to +11% YoY, so the comp is not unusually tough.


Guidance and Management Commentary

Latest Guidance (as of Q2 2026)

MetricFY 2026 Guidance (Q2)Q3 2026 GuidanceNotes
Revenue ($M)67,60017,200Raised $300M in Q2; up $600M YTD
Adj. EPS13.87–14.073.84–3.88Includes $0.14 dilution from Apogee deal
Skyrizi Sales ($M)21,700
Raised $100M in Q2
Neuroscience Sales12,700
Raised $100M in Q2
Op Margin (%)~47%~50% (Q3)Margin expansion continues
R&D Expense ($M)9,800
Up $100M for Apogee pipeline investments
Net Interest Expense2,900
Up $200M for Apogee financing
Tax Rate (%)14.5

Management Commentary — Key Themes

  • Immunology: Skyrizi and Rinvoq continue to outperform, with robust capture rates and share gains. Subcutaneous induction for Skyrizi in Crohn’s is expected to be a significant catalyst.
  • Neuroscience: Now a top-tier growth driver; Parkinson’s (Vyalev, tavapadon), migraine, and psychiatry all delivering strong results.
  • Oncology: Etentamig (BCMA TCE) and Temab-A (ADC) are highlighted as underappreciated assets with upcoming pivotal data.
  • Aesthetics: Market remains soft, especially in fillers, but new product launches (Boey) and innovation are expected to support long-term growth.
  • Pipeline: Apogee acquisition adds late-stage and mid-stage immunology/respiratory assets; focus on rapid integration and pipeline prioritization.
  • Margins: Operating leverage expected to continue as revenue grows faster than expenses.
  • Pricing: Immunology pricing headwinds remain “low single digits”; payer negotiations for 2027 are ongoing but consistent with prior years.

Summary and Conclusions

  • AbbVie enters Q3 2026 earnings with strong momentum: Double-digit revenue and EPS growth, multiple guidance raises YTD, and continued outperformance in immunology and neuroscience.
  • Key focus areas for the print: Skyrizi and Rinvoq growth sustainability, neuroscience outperformance, progress on Skyrizi subcu induction approval, Apogee pipeline integration, and pivotal HS/oncology readouts.
  • YoY comp is not unusually tough: Q3 2025 was a strong quarter, but consensus expects an acceleration in growth, reflecting confidence in the current portfolio.
  • Guidance risk appears to the upside: Management has consistently raised guidance throughout 2026; further upward revisions or positive commentary on pipeline catalysts would be well received.
  • Margin expansion and capital allocation: Operating leverage is a tailwind; Apogee deal is not expected to constrain further BD or dividend growth.

Bottom Line: The most important factors for Q3 2026 are continued robust growth in Skyrizi/Rinvoq and neuroscience, updates on key pipeline catalysts (especially Skyrizi subcu, HS, oncology, Apogee), and any further upward revisions to guidance. The company is coming off a strong Q3 2025 but faces a manageable comp given the current momentum and portfolio strength.

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